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Adrian Drazic
Buchner Lab
Lichtenberstr. 4
08928913191
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- Protection mechanism of Escherichia coli against oxidative stress (especially HOCl stress)

- Characterization of the HOCl-specific transcritpion factor YjiE

- Changes in metabolic pathways upon oxidative stress (methods: GCMS and NMR)

Gebendorfer KM*, Drazic A*, Le Y, Gundlach J, Bepperling A, Kastenm├╝ller A, Ganzinger KA, Braun N, Franzmann TM, Winter J. Identification of a hypochlorite-specific transcription factor from Escherichia coli. J Biol Chem. 212 Feb 24;287(9),6892-6903.

* authors contributed equally

Drazic A, Tsoutsoulopoulus A, Peschek J, Gundlach J, Krause M, Bach NC, Gebendorfer KM, Winter J. Role of cysteines in the stability and DNA-binding activity of the hypochlorite-specific transcription factor HypT. PLoS ONE 2013 doi: 10.1371/journal.pone.0075683.

Drazic A, Miura H, Peschek J, Ye Y, Bach NC, Kriehuber T, Winter J. Methionine oxidation activates a transcription factor in response to oxidative stress. Proc Natl Acad Sci USA 2013 doi: 10.1073/pnas.1300578110.

Drazic A, Gebendorfer KM, Mak S, Steiner A, Krause M, Bepperling A, Winter J. Tetramers are the activation-competent species of the HOCl-specific transcription factor HypT. J Biol Chem. 289:977-86. doi: 10.1074/jbc.M113.521401.



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Adrian Drazic
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